Yes they have had success in the NFL, but it's only been one year. Remember Michael Vick when he first came out? He was a sensation. Big arm, big speed, but eventually the league caught up to him and he broke down among other things. Remember the wild cat? It was all the rage years ago and it has died down too. If these need breed qb's have sustained success in the NFL great, but I don't think they will The read option was successful this year because team's were not ready for it. Just like the wildcat. RGIII is already broken. Wilson, while a very good qb, won with a great running game and defense. Kapernick is a very good qb overall. Nothing negative to say about him really. In the end, pro style qb's will generally always be more successful than hybrid qb's.
Another thing about the different style of offenses. If you run a pro style offense in college, you will be more adept to the NFL game than someone who runs the spread option out of the shotgun. A lot of qb's struggle with that transition in the NFL.